Throughout our lives, our bones are continually being remodelled in two steps: the “breakdown” of of bone (resorption) and replacement of the removed bone by new bone (formation). In osteoporosis, the bones are weakened because the breakdown occurs at a faster rate than the rebuilding. When bone is resorbed, fragments of the bone collagen are released into the bloodstream. One of these fragments is called “C-telopeptide.” This test is used to assess the loss of bone mass (bone resorption) in cases of osteoporosis or other bone diseases such as Paget’s disease.
C-reactive protein (CRP) is a protein produced by the liver. Normally, you have low levels of C-reactive protein in your blood. Your liver releases more CRP into your bloodstream if you have inflammation in your body. High levels of CRP indicate you have a serious health condition that's causing the inflammation.