. Beta-crosslaps is the carboxy-terminal telopeptide (CTX) fragment of type I collagen that is released into the bloodstream during the process of bone resorption by the osteoclasts.
. Elevated levels of Beta-crosslaps are associated with increased bone resorption, which can be seen in osteoporosis, Paget's disease, and other bone metabolic disorders.
. The test is particularly useful for monitoring treatment response in patients undergoing therapy.