dsDNA Ab

Double-stranded DNA antibodies (ds-DNA Ab) are found primarily in systemic lupus erythematosus (SLE) and are important but not entirely sufficient for diagnosing the condition. Such antibodies are present in 80% to 90% of SLE cases. They are also found in smaller fractions of patients with other rheumatic disorders and chronic active hepatitis, mononucleosis, and biliary cirrhosis.