SPOT-MAS 5 Early Screening For 5 Common Cancers is a non-invasive blood test that uses next-generation sequencing (NGS) technology to analyze circulating tumor DNA (ctDNA) in the blood. This test can detect 5 common cancers at a very early stage, including lung, liver, colorectal, stomach, and esophageal cancers. SPOT-MAS 5 is recommended for people at high risk for cancer, such as those over 40, those with a family history of cancer, those who smoke, or those exposed to other risk factors.