Sex Hormone-binding Globulin (SHBG) is a protein that sticks to sex hormones in your blood, preventing your body from using them. Your body can only use sex hormones that are not attached to SHBG. The SHBG test is mostly used to see how testosterone is working in your body. For men, it checks how much testosterone is available for the body to use, which can indicate problems like hormone imbalances or issues with having children. For women, SHBG does something similar but looks at how this protein handles both testosterone and estrogen. Even though women produce less testosterone, knowing about SHBG is important for women's health and how they feel overall. High levels of SHBG in women can make less testosterone and estrogen available, which can affect many things, including having children and bone health. This test can help doctors understand women's hormone levels and diagnose conditions like PCOS, early puberty, and menopause symptoms. Understanding SHBG levels in women is important for both reproductive and overall health.