. CCP Ab are autoantibodies directed against specific proteins in the body. The presence of CCP Ab in the blood is highly specific to rheumatoid arthritis (RA), and their detection can help confirm a diagnosis, especially in early stages and in patients with joint symptoms but no obvious signs of inflammation.
. CCP Ab test is considered more specific than rheumatoid factor (RF) for diagnosing RA and particularly identifying patients who may be at higher risk for more aggressive disease and joint damage.
. The test can also be used to monitor disease activity and guide treatment decisions, helping clinicians tailor therapy to prevent joint destruction and improve long-term outcomes.
. CCP Ab can also be present in other autoimmune conditions, so the result must be interpreted in conjunction with clinical symptoms and other diagnostic tests.