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If DIAG’s lab receives the sample before 10:00 AM (Mon & Thu), test results will be available by 10:00 AM four days later.
If DIAG’s lab receives the sample after 10:00 AM (Mon – Thu), test results will be available by 10:00 AM seven days later.
Pregnant women need to bring their most recent ultrasound results to DIAG for consultation before the test. There are no specific timing requirements for NIPT.
The NIPT test at DIAG is conducted through 7 steps:
- Step 1: Consultation with doctors & Completion of Consent Form
- Step 2: Blood sample collection & Transport to the laboratory
- Step 3: Sample reception & Processing
- Step 4: Whole Genome Sequencing with DNBSEQ™ Technology
- Step 5: Bioinformatics analysis using HALOS software
- Step 6: Results Delivery via Zalo/SMS/Website
- Step 7: Genetic Counseling
You can learn more about the 7-step NIPT procedure here: https://diag.vn/en/pregnancy/nipt-procedure-at-diag-medical-center/
NIPT has a higher accuracy rate compared to other prenatal screening methods (such as the Double Test, Triple Test).
- Over 99% – Superior detection accuracy.
- Only 0.1% – Extremely low false-positive rate.
- Early detection from the 10th week of Pregnancy.
- Comprehensive screening for over 100 chromosomal abnormalities.
- Single blood sample – No need for additional Karyotyping.
- Non-invasive and Safer than invasive procedures.
You can learn more about the Advantages of NIPT compared to other traditional prenatal screening methods here: https://diag.vn/en/pregnancy/what-is-nipt-advantages-of-nipt-over-traditional-prenatal-screening/
The NIFTY® technology, developed by BGI Genomics, has been validated through the largest global research study, with over 146,000 test samples from more than 500 medical centers. The research results show that NIPT testing using NIFTY® technology has an extremely low false positive rate of less than 0.05%.
Currently, NIFTY® enhances the ability to detect over 100 chromosomal abnormalities, including chromosomal number abnormalities and various microdeletions/duplications.
You can learn more about NIFTY® technology in NIPT testing here: https://diag.vn/en/pregnancy/nipt-with-nifty-technology-at-diag-an-advanced-prenatal-screening-solution/
No. NIPT cannot detect all genetic disorders (including inherited diseases or congenital defects). NIPT can only screen for certain specific conditions related to chromosomal abnormalities.
NIPT helps detect many numerical chromosomal abnormalities (aneuploidy), including:
- Down Syndrome: caused by the presence of three copies of chromosome 21.
- Edwards Syndrome: caused by an extra copy of chromosome 18.
- Patau Syndrome: caused by the presence of three copies of chromosome 13.
- Turner Syndrome: only affects females and occurs when they have only one X chromosome.
- Jacobs Syndrome: affects males and occurs when they have an extra Y chromosome.
- Klinefelter Syndrome: only affects males and occurs when they have an extra X chromosome.
- Triple X Syndrome: affects females, occurring when they have three X chromosomes.
- Severe variants of Klinefelter Syndrome: occur when males inherit more than two X chromosomes.
You can refer to the List of numerical chromosomal abnormalities that may occur in the fetus here: https://diag.vn/en/pregnancy/chromosomal-abnormalities/
NIPT can early detect over 90 structural chromosomal abnormalities, including syndromes caused by chromosomal deletions or duplications.
- 1p36 Deletion Syndrome
- 4p16.3 Deletion Syndrome
- Cri-du-Chat Syndrome
- 7q11.23 Deletion Syndrome
- Prader-Willi Syndrome
- Angelman Syndrome
- Smith-Magenis Syndrome
- DiGeorge Syndrome
In addition to chromosomal abnormalities, preeclampsia is one of the leading causes of illness and death for both mothers and newborns. According to official statistics and scientific reports, approximately 76,000 maternal deaths and over 500,000 neonatal deaths occur annually worldwide due to preeclampsia.
Therefore, it is particularly important to perform both NIPT and preeclampsia tests simultaneously. This aids in early detection of risks that can seriously affect the mother’s health and ensures the healthy development of the fetus.
Double Test and Triple Test are suitable alternatives in case NIPT is not required or affordable. Diag offers fetal defect screening services at the following prices:
- Double Test: 384,000 VND
- Triple Test: 450,000 VND
Experts recommend that pregnant women undergo NIPT. To determine if NIPT is suitable for you, you should consider the following 4 factors:
- 100% safe: NIPT is asbolutely safe for both the mother and the fetus. Unlike amniocentesis, NIPT does not pose risks such as miscarriage, stillbirth, preterm birth, vaginal bleeding, or infection.
- Highly accurate: NIPT has high accuracy up to 99.9% but is only a screening test. However, as it is a screening test, confirmatory diagnosis through amniocentesis is necessary if a high risk of abnormalities is detected.
- Fast results: NIPT results are available within 5 working days, whereas amniocentesis takes 10 to 14 days.
- Cost-effective: DIAG’s NIPT Panels range from 1,500,000 to 7,500,000 VND, whereas amniocentesis costs 10,000,000 VND or more.
A low-risk NIPT result means that the likelihood of the fetus having chromosomal abnormalities is very low. However, a low-risk result does not guarantee that the fetus will not have chromosomal abnormalities. Therefore, it is important to attend regular prenatal check-ups and undergo additional tests as advised by doctors.
If the NIPT result indicates a high risk for a chromosomal abnormality, it does not mean that the fetus will definitely have that chromosomal abnormality.
NIPT is a screening test, not a diagnostic test. Therefore, you should consult with a doctor to undergo further diagnostic steps for more detailed evaluation, such as amniocentesis or chorionic villus sampling.
Currently, there is no method to completely eliminate the risks that cause chromosomal number abnormalities. However, medical experts recommend that women planning to conceive should undergo preconception health check-ups, maintain a healthy lifestyle, and consult with a genetic specialist if there is a family history of genetic disorders or if they have risk factors.
DIAG provides financial support of up to 4.5 million VND for pregnant women with “high risk” or “detected” NIPT results. Pregnant women with “low risk,” “not detected” or “no result” NIPT results are also eligible for financial support under DIAG’s specific policy.
