Mysterious Acute Hepatitis in Children – Ministry of Health Suggests Close Monitoring Units

Up to now, Vietnam has not recorded any case of a child suffering from ‘mysterious’ acute hepatitis. The Ministry of Health said that it has asked the units to closely monitor; Coordinate with the locality to analyze suspected cases of acute hepatitis of unknown cause and immediately report unusual cases…

In the face of the increasing development of “mysterious” cases of acute hepatitis, although so far Vietnam has not recorded any cases, on the afternoon of May 8, the Ministry of Health said that it has increased the work of directing, inspection and supervision, requesting units to closely monitor, summarize the situation, and analyze the epidemiology of acute hepatitis of unknown cause in the world;

Coordinate with localities to analyze suspected cases of acute hepatitis of unknown cause and immediately report unusual cases, at the same time assess risks and propose preventive measures in Vietnam.

Previously, the Department of Preventive Medicine, the Ministry of Health had sent a document to the Central Institute of Hygiene and Epidemiology; Pasteur Institute Nha Trang; Pasteur Institute Ho Chi Minh City; Central Highlands Institute of Hygiene and Epidemiology on strengthening surveillance of acute hepatitis of unknown etiology in children.

The above units are also required to strengthen the direction, inspection and supervision, to support localities and units to implement the surveillance, prevention and testing of hepatitis virus, with a focus on vaccination activities. hepatitis B vaccine for infants, children under one year of age and high-risk subjects, ensuring safety and reaching the coverage rate according to the planned targets.

The Department of Preventive Medicine said that, according to updated information from the World Health Organization, this disease occurs in children from 1 month old to 16 years old, most children recover completely, but there are some cases. In severe cases, nearly 10% of cases require liver transplantation. The cases identified as acute hepatitis above presented with abdominal pain, diarrhea, vomiting and markedly elevated liver enzymes.

The majority of reported cases were without fever and undetected infection with common viruses that cause acute viral hepatitis (hepatitis A, B, C, D and E viruses). The World Health Organization and the European Centers for Disease Prevention and Control say the exact cause of hepatitis in these children is not known and investigations are ongoing. However, cases have occurred in areas where the adenovirus is high.

The Department of Health of Ho Chi Minh City has also requested medical facilities, especially pediatric hospitals, to strengthen detection of children with acute hepatitis.

Hospitals need to consult with the Ho Chi Minh City Hospital for Tropical Diseases and the Oxford University Clinical Research Unit (OUCRU) to collect information and samples, conduct PCR testing techniques, and metagenomics techniques to find agents. infectious agents such as adenovirus and other agents (if any).

At the National Children’s Hospital, Assoc. Prof. Dr. Tran Minh Dien, Director of the Hospital, said that the hospital had recorded some cases of liver damage, but it was in the group related to children with multi-system inflammatory syndrome (syndrome). MIS-C) following COVID-19 infection, no cases of isolated liver injury or adenovirus-associated liver injury have been reported.

At the National Hospital for Tropical Diseases, BSCKII Nguyen Nguyen Huyen – Head of the Kim Chung Medical Examination Department (Dong Anh) said that following the direction of the Ministry of Health, to strengthen surveillance and early detection of inflammatory diseases. acute liver disease of unknown cause in children, during the examination at the Hospital, doctors have exploited more information, trying to detect the early signs and symptoms of suspected hepatitis – the most is for children with signs of vomiting, nausea, abdominal pain, diarrhea, whether the child has hepatitis (based on liver enzyme tests) or has signs of yellow urine, yellow eyes, fulminant liver failure…

According to the World Health Organization, as of May 7, there were about 278 children with ‘mysterious’ acute hepatitis in 20 countries, 9 deaths.

Source: Bộ Y tế: Theo dõi chặt chẽ bệnh viêm gan cấp tính ‘bí ẩn’ ở trẻ, báo cáo ngay trường hợp bất thường – Hoạt động của địa phương – Cổng thông tin Bộ Y tế (

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